Screening of antimycotic activity of plants used in Guatemala for the treatment of Dermatophytoses
DOI:
https://doi.org/10.33885/sf.1991.3.772Abstract
By ethnobotanical survey and literature review 100 plants were detected as being used
in Guatemala for the treatment of dermatophytoses; from these a sample of 50 plants was
screened for antidermatophyte activity. Results showed that aqueous extracts of 25 plants
inhibit one or more dermatophytes (Epidermophyton f/occosum, Microsporum canis, M.
gypseum, Trichophyton mentagrophytes and T. rubrum). The most commonly inhibited
dermatophytes were E. floccosum (36%), T. rubrum (32%) and T. menragrophytes (29%);
less inhibited were M. canis (24%) and M. gypseum (23%). American plants which exhibited
the best activity were: Byrsonima crassifolia, Cassia grandis, C. occidenta/is, Diphysa
canhagenensis, D. robinioides, Gliricidia sepium, Piscidiapiscipula, Smilax regelii, Solanum
americanum and S. nigrescens. Fungicidal and fungistatic activity was demonstrated, as well
as the minimal inhibitory concentration. Results support a scientific basis for the use of these
plants for the treatment of dermatophyte infections in man.
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